J Korean Soc Endocrinol.  1995 Dec;10(4):445-450.

A Case of Isolated ACTH Deficiency

• Kim SJ
• Choi KM
• Baik SH
• Choi DS

Abstract

solated ACTH deficiency is a very uncommon cause of hypoadrenocorticism, with less than 200 cases reported in the literatures. The clinical presentation can be similar to that of primary adrenal insufficiency, but there is a greater tendency for hypoglycemia and absence of hyperpigmentation. The diagnosis is established by demonstrating hypocortisolism with undetectable serum levels of ACTH, normal adrenal responsiveness to prolonged ACTH infusion, and an absent ACTH response to insulin-induced hypoglycemia. Other endocrine function is normal.We experienced a case of isolated ACTH deficiency in 34 years old female who was admitted due to fever and drowsy mentality.So we present this case with a review of literatures.

MeSH Terms

Addison Disease
Adrenocorticotropic Hormone*
Diagnosis
Female
Fever
Humans
Hyperpigmentation
Hypoglycemia
Adrenocorticotropic Hormone