Korean J Otorhinolaryngol-Head Neck Surg.  2019 Sep;62(9):520-523. 10.3342/kjorl-hns.2018.00661.

A Case of Langerhans Cell Sarcoma Presenting as Submandibular Gland Mass

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Chungnam National University, Daejeon, Korea. bskoo515@cnuh.co.kr

Abstract

Langerhans cell sarcoma is a rare, proliferative tumor of Langerhans cells, which shows cytologic characteristics and clinical features of malignant tumor. Langerhans cell sarcoma primarily occurs in lymph nodes, skin, lung, liver, and spleen. However, very few cases have been reported in the head and neck region. Because of its rarity, an optimal treatment approach is unknown; however, Langerhans cell sarcoma grows aggressively and shows a poor prognosis, such that a more aggressive and multi-modality treatment approach is necessary. Here, we report the case of a 36-year-old male with Langerhans cell sarcoma, who presented with a mass in the submandibular gland area and was treated with wide excision and postoperative radiotherapy.

Keyword

Langerhans cells; Sarcoma; Treatment

MeSH Terms

Adult
Head
Humans
Langerhans Cell Sarcoma*
Langerhans Cells
Liver
Lung
Lymph Nodes
Male
Neck
Prognosis
Radiotherapy
Sarcoma
Skin
Spleen
Submandibular Gland*
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