Int Neurourol J.  2019 Sep;23(3):219-225. 10.5213/inj.1938032.016.

Artificial Urinary Sphincter Cuff Size Predicts Outcome in Male Patients Treated for Stress Incontinence: Results of a Large Central European Multicenter Cohort Study

Affiliations
  • 1Department of Urology and Pediatric Urology, University Hospital of Muenster, Muenster, Germany. fabiqu@gmx.de
  • 2Department of Urology and Pediatric Urology, University Medical Center of Johannes Gutenberg University, Mainz, Germany.
  • 3Department of Urology, Ludwig-Maximilians University Hospital, Großhadern Campus, Munich, Germany.
  • 4Department of Urology, Pediatric Urology, and Neurourology, University Hospital of Bonn, Bonn, Germany.
  • 5Department of Urology, Vivantes Hospital Am Urban, Berlin, Germany.
  • 6Department of Urology, Lueneburg Hospital, Lueneburg, Germany.
  • 7Department of Urology, Goettlicher Heiland Hospital of Vienna, Vienna, Austria.
  • 8Department of Urology, Bethel Evangelical Hospital, Bielefeld, Germany.
  • 9Department of Urology and Pediatric Urology, University Hospital of Kiel, Kiel, Germany.
  • 10Department of Urology, Diaconal Hospital of Stuttgart, Stuttgart, Germany.
  • 11Department of Urology and Pediatric Urology, University Hospital of Heidelberg, Heidelberg, Germany.
  • 12Department of Urology, Diaconal Hospital of Schwaebisch Hall, Schwaebisch Hall, Germany.
  • 13Department of Urology and Robotic Surgery, Prosper-Hospital, Recklinghausen, Germany.
  • 14Department of Urology, St. Bernward Hospital Hildesheim, Hildesheim, Germany.
  • 15Department of Urology and Pediatric Urology, Helios Hospital Duisburg, Duisburg, Germany.
  • 16Department of Urology and Pediatric Urology, St. Barbara Hospital Hamm GmbH, Hamm, Germany.
  • 17Department of Urology and Pediatric Urology, Helios Hospital Schwelm, Schwelm, Germany.
  • 18Department of Urology and Pediatric Urology, Westpfalz Medical Center, Kaiserslautern, Germany.

Abstract

PURPOSE
The aim was to study the correlation between cuff size and outcome after implantation of an AMS 800 artificial urinary sphincter.
METHODS
A total of 473 male patients with an AMS 800 sphincter implanted between 2012 and 2014 were analyzed in a retrospective multicenter cohort study performed as part of the Central European Debates on Male Incontinence (DOMINO) Project.
RESULTS
Single cuffs were implanted in 54.5% and double cuffs in 45.5% of the patients. The cuffs used had a median circumference of 4.5 cm. Within a median follow of 18 months, urethral erosion occurred in 12.8% of the cases and was associated significantly more often with small cuff sizes (P<0.001). Multivariate analysis showed that, apart from cuff size (P=0.03), prior irradiation (P<0.001) and the penoscrotal approach (P=0.036) were associated with an increased erosion rate. Continence rate tended to be highest with median cuff sizes (4-5.5 cm).
CONCLUSIONS
Apart from irradiation and the penoscrotal approach, small cuff size is a risk factor for urethral erosion. Results are best with cuff sizes of 4.5-5.5 cm.

Keyword

Artificial urinary sphincter; AMS 800; Cuff size; Male; Stress urinary incontinence; Single or double cuff

MeSH Terms

Cohort Studies*
Humans
Male*
Multivariate Analysis
Retrospective Studies
Risk Factors
Urinary Sphincter, Artificial*
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