J Korean Orthop Assoc.  1978 Sep;13(3):439-444. 10.4055/jkoa.1978.13.3.439.

Pigmented Villonodular Synovitis: Report of four cases

• Jahng JS
• Kang MK

• KMID: 2460352
• DOI: http://doi.org/10.4055/jkoa.1978.13.3.439

Abstract

Pigmented villonodular synovitis is a kind of benigh inflammatory lesion involving synovial membrane, characterized by yellowish or yellow-grayish colored villous nodules of synovial membrane, formed by accumulation of cholesterol and hemosiderin with numerous cleftings of synovial membrane. The lesion was first described by Chassaignac (1852) as the nodular form arising in relation to the flexor tendon sheath of the middle and index fingers. After that Simon (1865) described it as a xanthoma of the synovia, and there after various names were given by many authors, according to the characteristics of the pathologic fetures. In 1941 Jaffe named this lesion pigmented villonodular synovitis, which is now generally accepted. Still the direct cause of this lesion is not clearly known, but chronic stimulation of synovia is generally accepted as an etiologic factor. In this paper we report four cases of pigmented villonodular synovitis, which were diagnosed and treated in our department. One of the four cases occurred at the proximal tibiofibula joint which is a very rare site.

MeSH Terms

Cholesterol
Fingers
Hemosiderin
Joints
Synovial Fluid
Synovial Membrane
Synovitis, Pigmented Villonodular*
Tendons
Xanthomatosis
Cholesterol
Hemosiderin