Clin Mol Hepatol.
2019 Sep;25(3):294-304. 10.3350/cmh.2018.0086.
Effects of different exercise modalities on novel hepatic steatosis indices in overweight women with type 2 diabetes
- Affiliations
-
- 1Department of Sport Sciences, Faculty of Humanities, Shahrekord University, Shahrekord, Iran. banitalebi.e@gmail.com
- 2Department of Exercise Physiology, Faculty of Sport Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
- KMID: 2459791
- DOI: http://doi.org/10.3350/cmh.2018.0086
Abstract
- BACKGROUND/AIMS
Fatty liver is a clinical and pathologic condition in individuals with type 2 diabetes (T2D). The purpose of this study is to examine the effects of different exercise modalities on non-alcoholic fatty liver indices (fatty liver index [FLI], lipid accumulation product [LAP], hepatic steatosis index [HSI], and Framingham Steatosis Index [FSI]) in women with T2D.
METHODS
Fifty-two women with T2D and a mean age of 55.07±5.92 yrs, body mass index (BMI) 28.94±4.09 kg/m² , and hemoglobin A1c (HbA1c) 9.41±0.82% were randomized to a sprint interval training (SIT) (n=17), combined aerobic and resistance (A+R) training (n=17), or control group (n=18) for 10 weeks. Two-way repeated analysis of variance (ANOVA) was used to find differences between groups and the effects of time and Time×Group interactions after 10 weeks on non-alcoholic fatty liver indices. After this, ANOVA models were constructed to determine the effects of group allocation and change in non-alcoholic fatty liver indices.
RESULTS
There were significant time interactions for FLI (P<0.001), HSI (P<0.001), and LAP (P<0.001). Also, there were significant Time×Group interactions for fasting blood glucose (P=0.034), and HbA1c (P=0.006).
CONCLUSIONS
Results highlight that exercise training, independent of mode of training, is an effective strategy to improve some indices related to hepatic steatosis and blood glucose profiles in women with T2D.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Diagnostic Performance of Hepatic Steatosis Algorithms in Korean Population with Metabolic-Associated Fatty Liver Disease
- Management of Patients with Nonalcoholic Fatty Liver Disease with Lifestyle Modification
- Greater Severity of Steatosis Is Associated with a Higher Risk of Incident Diabetes: A Retrospective Longitudinal Study
- Approach to Fatty Liver Disease in Patients with Type 2 Diabetes
- The independent effect of exercise on biopsy-proven non-alcoholic fatty liver disease: A systematic review
