J Rheum Dis.  2019 Oct;26(4):282-285. 10.4078/jrd.2019.26.4.282.

A Rare Case of Overlap Syndrome with Diffuse Systemic Sclerosis, Rheumatoid Arthritis, and Cutaneous Sarcoidosis

Affiliations
  • 1Division of Rheumatology, Department of Internal Mediciney, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. min6403@catholic.ac.kr
  • 2Department of Pathology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Abstract

Overlap syndrome is defined as a disease entity that satisfies the classification criteria of at least two connective tissue diseases occurring concurrently or separately in a single patient. Here, we report a rare case of a 59-year-old woman with diffuse systemic sclerosis with lung involvement-rheumatoid arthritis overlap syndrome accompanied by cutaneous sarcoidosis. Although there is no consensus for the optimal treatment of overlap syndrome to date, this case of co-existing rheumatoid arthritis and systemic sclerosis with interstitial lung disease successfully responded to abatacept.

Keyword

Undifferentiated connective tissue diseases; Systemic sclerosis; Rheumatoid arthritis; Sarcoidosis

MeSH Terms

Abatacept
Arthritis
Arthritis, Rheumatoid*
Classification
Connective Tissue Diseases
Consensus
Female
Humans
Lung
Lung Diseases, Interstitial
Middle Aged
Sarcoidosis*
Scleroderma, Diffuse*
Scleroderma, Systemic
Abatacept
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