Korean J Rehabil Nurs.  2019 Jun;22(1):15-26. 10.7587/kjrehn.2019.15.

Effects of Subjective Memory Complaints, Depression and Executive Function on Activities of Daily Living in Individuals with Mild Cognitive Impairment

• Jung MS
• Oh EY
• Chung EY

• KMID: 2457663
• DOI: http://doi.org/10.7587/kjrehn.2019.15

Abstract

PURPOSE
This study aimed to examine the effects of subjective memory complaints, depression and cognitive function on performance of activities of daily living (ADL) in individuals with mild cognitive impairment (MCI).
METHODS
A total sample consisted of 250 MCI patients diagnosed within one year. All participants were assessed with a battery of standardized neuropsychological tests, self-report measures of subjective memory complaints and depression, and performance of basic and instrumental ADL. Correlational and multiple linear regression analyses were conducted to identify the factors associated with performance of basic and instrumental ADL, respectively.
RESULTS
Executive function and depression explained 9.4% of the variance in basic ADL. Reduced executive function and greater depressed mood were associated with worse performance on basic ADL. Executive function, subjective memory complaints, and time since onset of cognitive symptoms accounted for 22.2% of the variance in instrumental ADL in individuals with MCI. Lower executive function (t=−2.02, p=.044), greater memory complaints (t=5.36, p<.001), and longer periods of experiencing cognitive symptoms (t=2.24, p=.026) were associated with worse instrumental ADL performance.
CONCLUSION
These results may help healthcare professionals develop interventions to improve cognitive outcomes with better understanding of the relationship among cognition, mood, and behavioral performance in individuals with MCI.

Keyword

Memory disorders; Depression; Executive function; Activities of daily living; Cognitive dysfunction

MeSH Terms

Activities of Daily Living*
Cognition
Delivery of Health Care
Depression*
Executive Function*
Humans
Linear Models
Memory Disorders
Memory*
Mild Cognitive Impairment*
Neurobehavioral Manifestations
Neuropsychological Tests