Clin Endosc.  2019 Jul;52(4):321-327. 10.5946/ce.2019.072.

Assessment of Endoscopic Gastric Atrophy according to the Kimura-Takemoto Classification and Its Potential Application in Daily Practice

Affiliations
  • 1Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam. drquachtd@ump.edu.vn
  • 2Department of Gastroenterology, Gia- Dinh People’s Hospital, Ho Chi Minh City, Vietnam.
  • 3Health Service Center, Hiroshima University, Higashihiroshima, Hiroshima, Japan.

Abstract

The assessment of endoscopic gastric atrophy (EGA) according to the Kimura-Takemoto classification has been reported to correlate well with histological assessment. Although agreement among beginner endoscopists was less than that among experienced endoscopists, it has been shown that agreement level could markedly improve and remained stable after proper training. Several cohort studies have consistently shown that the severity of EGA at baseline is significantly associated with the presence of advanced precancerous gastric lesions and gastric cancer, as well as the development of gastric cancer in future. Patients with moderate-to-severe EGA still have high risk of gastric cancer even after successful Helicobacter pylori eradication and should be candidates for gastric cancer surveillance. The assessment of EGA, therefore, could be used as a preliminary tool to identify individuals at high risk for gastric cancer. In this paper, we review the agreement on mucosal atrophy assessment between the Kimura-Takemoto classification and histology as well as the potential application of this endoscopic classification to identify precancerous gastric lesions and gastric cancer in daily practice.

Keyword

Gastric cancer; Endoscopy; Helicobacter pylori; Surveillance; Screening

MeSH Terms

Atrophy*
Classification*
Cohort Studies
Endoscopy
Helicobacter pylori
Humans
Mass Screening
Stomach Neoplasms
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