Korean J Thorac Cardiovasc Surg.  2019 Jun;52(3):162-164. 10.5090/kjtcs.2019.52.3.162.

Ventricular Septal Defect Closure in a Neonate with Osteogenesis Imperfecta

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea. whiteuri@dsmc.or.kr
  • 2Department of Pediatrics, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.

Abstract

A male patient weighing 2.5 kg was admitted for respiratory difficulty, and a large ventricular septal defect (VSD) was diagnosed. During care, sudden right leg swelling with a femur shaft fracture occurred. The patient's father had a history of recurrent lower extremity fractures; thus, osteogenesis imperfecta was considered. The patient's respiratory difficulty became aggravated, and VSD repair in the neonatal period was therefore performed with gentle sternal traction and great vessel manipulation under total intravenous anesthesia to prevent malignant hyperthermia. The patient was discharged without notable problems, except minor wound dehiscence. Outpatient genetic testing revealed that the patient had a COL1A1/COL1A2 mutation.

Keyword

Osteogenesis imperfecta; Malignant hyperthermia; Cardiac surgery

MeSH Terms

Anesthesia, Intravenous
Fathers
Femur
Genetic Testing
Heart Septal Defects, Ventricular*
Humans
Infant, Newborn*
Leg
Lower Extremity
Male
Malignant Hyperthermia
Osteogenesis Imperfecta*
Osteogenesis*
Outpatients
Thoracic Surgery
Traction
Wounds and Injuries
Full Text Links
  • KJTCS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr