Korean J Ophthalmol.  2019 Aug;33(4):389-391. 10.3341/kjo.2018.0112.

Peripapillary Granuloma with Optic Nerve Head Involvement Associated with Sarcoidosis

Affiliations
  • 1Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea. I0377@paik.ac.kr

Abstract

No abstract available.


MeSH Terms

Granuloma*
Optic Disk*
Optic Nerve*
Sarcoidosis*

Figure

  • Fig. 1 A 40-year-old man with a history of tuberculosis presented for a medical evaluation after complaining of gradually decreased vision in his right eye for the past month. (A) Chest X-ray demonstrated bilateral hilar lymphadenopathy. (B) Fundus photography of the right eye at the initial visit revealed a nodular mass involving the optic nerve head surrounded by vitreous hemorrhaging and inflammatory cells. (C) Optical coherence tomography indicated subretinal fluid involving the macula with photoreceptor cell layer thinning. Fluorescein angiography showed hypofluorescence of the granuloma surrounded by tortuous vessels with (D) leakage in the early phase and (E) late leakage from the granuloma. Indocyanine green angiography revealed hypofluorescence of the lesion in both the (F) early and (G) late phases. The patient was diagnosed with sarcoidosis and treated with oral prednisolone and an intravitreal dexamethasone implant. (H) Follow-up fundus photography and (I) optical coherence tomography 6 months later demonstrated shrinkage of the granuloma and resolution of the subretinal fluid. Written informed consent was obtained from the patient.


Reference

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5. Kuppermann BD, Blumenkranz MS, Haller JA, et al. Randomized controlled study of an intravitreous dexamethasone drug delivery system in patients with persistent macular edema. Arch Ophthalmol. 2007; 125:309–317.
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