Ann Clin Neurophysiol.  2018 Jul;20(2):101-104. 10.14253/acn.2018.20.2.101.

Electrophysiological and radiological evidence for the multifocal nature of a case of multifocal acquired demyelinating sensory and motor neuropathy

• Seong GH
• Bae JS
• Ryu S

• KMID: 2454714
• DOI: http://doi.org/10.14253/acn.2018.20.2.101

Abstract

Multifocal acquired demyelinating sensory and motor (MADSAM) neuropathy is a variant of chronic acquired demyelinating polyneuropathy. A 65-year-old women presented with upper arm weakness. A nerve conduction study showed conduction blocks over intermediate segments with sparing of distal compound action potentials. Magnetic resonance imaging revealed asymmetric hypertrophy of the brachial plexus on the affected side. These findings represent important electrophysiological and radiological evidence of MADSAM neuropathy. The condition of the patient began to improve after starting intravenous immunoglobulin administration.

Keyword

Polyneuropathy, Chronic inflammatory demyelinating; Neural conduction; Magnetic resonance imaging

MeSH Terms

Action Potentials
Aged
Arm
Brachial Plexus
Female
Humans
Hypertrophy
Immunoglobulins
Magnetic Resonance Imaging
Neural Conduction
Polyneuropathies
Immunoglobulins

Figure

• 

  Fig. 1. Findings of the motor nerve conduction study of the right ulnar nerve. The distal motor latency and the compound muscle action potentials were normal at the wrist and below the elbow. Conduction block was observed between above and below the elbow. NCV, nerve conduction velocity.

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  Fig. 2. Brachial plexus magnetic resonance imaging (Short T1 Inversion Recovery Image, non-contrast enhanced) revealed fusiform hypertrophy of the right C5-C8 roots, and plexus was observed (arrows). No hypertrophy was observed on the left side.

Reference

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