Cancer Res Treat.  2016 Apr;48(2):427-435. 10.4143/crt.2015.478.

Robotic Surgery for Rectal Cancer: An Update in 2015

• Kwak JM
• Kim SH

• KMID: 2454318
• DOI: http://doi.org/10.4143/crt.2015.478

Abstract

During the last decade, robotic surgery for rectal cancer has rapidly gained acceptance among colorectal surgeons worldwide, with well-established safety and feasibility. The lower conversion rate and better surgical specimen quality of robotic compared with laparoscopic surgery potentially improves survival. Earlier recovery of voiding and sexual function after robotic total mesorectal excision is another favorable outcome. Long-term survival data are sparse with no evidence that robotic surgery offers major benefits in oncological outcomes. Although initial reports are promising, more rigorous scientific evaluation in multicenter, randomized clinical trials should be performed to definitely determine the advantages of robotic rectal cancer surgery.

Keyword

Rectal neoplasms; Robotics; Laparoscopy; Total mesorectal excision

MeSH Terms

Laparoscopy
Rectal Neoplasms*
Robotics
Surgeons

Reference

References

1. Binder J, Kramer W. Robotically-assisted laparoscopic radical prostatectomy. BJU Int. 2001; 87:408–10.

2. Lowrance WT, Eastham JA, Savage C, Maschino AC, Laudone VP, Dechet CB, et al. Contemporary open and robotic radical prostatectomy practice patterns among urologists in the United States. J Urol. 2012; 187:2087–92.

3. Holloway RW, Patel SD, Ahmad S. Robotic surgery in gynecology. Scand J Surg. 2009; 98:96–109.

4. Weber PA, Merola S, Wasielewski A, Ballantyne GH. Telerobotic-assisted laparoscopic right and sigmoid colectomies for benign disease. Dis Colon Rectum. 2002; 45:1689–94.

5. Delaney CP, Lynch AC, Senagore AJ, Fazio VW. Comparison of robotically performed and traditional laparoscopic colorectal surgery. Dis Colon Rectum. 2003; 46:1633–9.

6. Rawlings AL, Woodland JH, Vegunta RK, Crawford DL. Robotic versus laparoscopic colectomy. Surg Endosc. 2007; 21:1701–8.

7. deSouza AL, Prasad LM, Park JJ, Marecik SJ, Blumetti J, Abcarian H. Robotic assistance in right hemicolectomy: is there a role? Dis Colon Rectum. 2010; 53:1000–6.

8. D'Annibale A, Morpurgo E, Fiscon V, Trevisan P, Sovernigo G, Orsini C, et al. Robotic and laparoscopic surgery for treatment of colorectal diseases. Dis Colon Rectum. 2004; 47:2162–8.

9. Park SJ, Lee KY, Lee SH. Laparoscopic surgery for colorectal cancer in Korea: nationwide data from 2008~2013. J Minim Invasive Surg. 2015; 18:39–43.

10. Allemann P, Duvoisin C, Di Mare L, Hubner M, Demartines N, Hahnloser D. Robotic-assisted surgery improves the quality of total mesorectal excision for rectal cancer compared to laparoscopy: results of a case-controlled analysis. World J Surg. 2016; 40:1010–6.

11. Cho MS, Baek SJ, Hur H, Min BS, Baik SH, Lee KY, et al. Short and long-term outcomes of robotic versus laparoscopic total mesorectal excision for rectal cancer: a case-matched retrospective study. Medicine (Baltimore). 2015; 94:e522.

12. Kim YS, Kim MJ, Park SC, Sohn DK, Kim DY, Chang HJ, et al. Robotic versus laparoscopic surgery for rectal cancer after preoperative chemoradiotherapy: case-matched study of shortterm outcomes. Cancer Res Treat. 2016; 48:225–31.

13. Levic K, Donatsky AM, Bulut O, Rosenberg J. A comparative study of single-port laparoscopic surgery versus roboticassisted laparoscopic surgery for rectal cancer. Surg Innov. 2015; 22:368–75.

14. Serin KR, Gultekin FA, Batman B, Ay S, Kapran Y, Saglam S, et al. Robotic versus laparoscopic surgery for mid or low rectal cancer in male patients after neoadjuvant chemoradiation therapy: comparison of short-term outcomes. J Robot Surg. 2015; 9:187–94.

15. Yamaguchi T, Kinugasa Y, Shiomi A, Tomioka H, Kagawa H, Yamakawa Y. Robotic-assisted vs. conventional laparoscopic surgery for rectal cancer: short-term outcomes at a single center. Surg Today. 2015 Oct 19 [Epub]. http://dx.doi.org/10.1007/s00595-015-1266-4.

16. Park EJ, Cho MS, Baek SJ, Hur H, Min BS, Baik SH, et al. Longterm oncologic outcomes of robotic low anterior resection for rectal cancer: a comparative study with laparoscopic surgery. Ann Surg. 2015; 261:129–37.

17. Barnajian M, Pettet D 3rd, Kazi E, Foppa C, Bergamaschi R. Quality of total mesorectal excision and depth of circumferential resection margin in rectal cancer: a matched comparison of the first 20 robotic cases. Colorectal Dis. 2014; 16:603–9.

18. Ghezzi TL, Luca F, Valvo M, Corleta OC, Zuccaro M, Cenciarelli S, et al. Robotic versus open total mesorectal excision for rectal cancer: comparative study of short and long-term outcomes. Eur J Surg Oncol. 2014; 40:1072–9.

19. Ielpo B, Caruso R, Quijano Y, Duran H, Diaz E, Fabra I, et al. Robotic versus laparoscopic rectal resection: is there any real difference? A comparative single center study. Int J Med Robot. 2014; 10:300–5.

20. Tam MS, Abbass M, Abbas MA. Robotic-laparoscopic rectal cancer excision versus traditional laparoscopy. JSLS. 2014; 18:e2014.00020.

21. D'Annibale A, Pernazza G, Monsellato I, Pende V, Lucandri G, Mazzocchi P, et al. Total mesorectal excision: a comparison of oncological and functional outcomes between robotic and laparoscopic surgery for rectal cancer. Surg Endosc. 2013; 27:1887–95.

22. Fernandez R, Anaya DA, Li LT, Orcutt ST, Balentine CJ, Awad SA, et al. Laparoscopic versus robotic rectal resection for rectal cancer in a veteran population. Am J Surg. 2013; 206:509–17.

23. Kim JC, Yang SS, Jang TY, Kwak JY, Yun MJ, Lim SB. Open versus robot-assisted sphincter-saving operations in rectal cancer patients: techniques and comparison of outcomes between groups of 100 matched patients. Int J Med Robot. 2012; 8:468–75.

24. Kwak JM, Kim SH, Kim J, Son DN, Baek SJ, Cho JS. Robotic vs laparoscopic resection of rectal cancer: short-term outcomes of a case-control study. Dis Colon Rectum. 2011; 54:151–6.

25. Park JS, Choi GS, Lim KH, Jang YS, Jun SH. Robotic-assisted versus laparoscopic surgery for low rectal cancer: case-matched analysis of short-term outcomes. Ann Surg Oncol. 2010; 17:3195–202.

26. Bianchi PP, Ceriani C, Locatelli A, Spinoglio G, Zampino MG, Sonzogni A, et al. Robotic versus laparoscopic total mesorectal excision for rectal cancer: a comparative analysis of oncological safety and short-term outcomes. Surg Endosc. 2010; 24:2888–94.

27. Patriti A, Ceccarelli G, Bartoli A, Spaziani A, Biancafarina A, Casciola L. Short- and medium-term outcome of robot-assisted and traditional laparoscopic rectal resection. JSLS. 2009; 13:176–83.

28. Delgado S, Momblan D, Salvador L, Bravo R, Castells A, Ibarzabal A, et al. Laparoscopic-assisted approach in rectal cancer patients: lessons learned from >200 patients. Surg Endosc. 2004; 18:1457–62.

29. Dulucq JL, Wintringer P, Stabilini C, Mahajna A. Laparoscopic rectal resection with anal sphincter preservation for rectal cancer: long-term outcome. Surg Endosc. 2005; 19:1468–74.

30. Guillou PJ, Quirke P, Thorpe H, Walker J, Jayne DG, Smith AM, et al. Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial. Lancet. 2005; 365:1718–26.

31. Rottoli M, Bona S, Rosati R, Elmore U, Bianchi PP, Spinelli A, et al. Laparoscopic rectal resection for cancer: effects of conversion on short-term outcome and survival. Ann Surg Oncol. 2009; 16:1279–86.

32. Resch A, Langner C. Lymph node staging in colorectal cancer: old controversies and recent advances. World J Gastroenterol. 2013; 19:8515–26.

33. Quirke P, Durdey P, Dixon MF, Williams NS. Local recurrence of rectal adenocarcinoma due to inadequate surgical resection: histopathological study of lateral tumour spread and surgical excision. Lancet. 1986; 2:996–9.

34. Wibe A, Rendedal PR, Svensson E, Norstein J, Eide TJ, Myrvold HE, et al. Prognostic significance of the circumferential resection margin following total mesorectal excision for rectal cancer. Br J Surg. 2002; 89:327–34.

35. Compton CC, Fielding LP, Burgart LJ, Conley B, Cooper HS, Hamilton SR, et al. Prognostic factors in colorectal cancer. College of American Pathologists Consensus Statement 1999. Arch Pathol Lab Med. 2000; 124:979–94.

36. Nagtegaal ID, van de Velde CJ, van der Worp E, Kapiteijn E, Quirke P, van Krieken JH, et al. Macroscopic evaluation of rectal cancer resection specimen: clinical significance of the pathologist in quality control. J Clin Oncol. 2002; 20:1729–34.

37. Baik SH, Kwon HY, Kim JS, Hur H, Sohn SK, Cho CH, et al. Robotic versus laparoscopic low anterior resection of rectal cancer: short-term outcome of a prospective comparative study. Ann Surg Oncol. 2009; 16:1480–7.

38. Ficarra V, Novara G, Artibani W, Cestari A, Galfano A, Graefen M, et al. Retropubic, laparoscopic, and robot-assisted radical prostatectomy: a systematic review and cumulative analysis of comparative studies. Eur Urol. 2009; 55:1037–63.

39. Novara G, Ficarra V, Mocellin S, Ahlering TE, Carroll PR, Graefen M, et al. Systematic review and meta-analysis of studies reporting oncologic outcome after robot-assisted radical prostatectomy. Eur Urol. 2012; 62:382–404.

40. Coelho RF, Rocco B, Patel MB, Orvieto MA, Chauhan S, Ficarra V, et al. Retropubic, laparoscopic, and robot-assisted radical prostatectomy: a critical review of outcomes reported by high-volume centers. J Endourol. 2010; 24:2003–15.

41. Akasu T, Sugihara K, Moriya Y. Male urinary and sexual functions after mesorectal excision alone or in combination with extended lateral pelvic lymph node dissection for rectal cancer. Ann Surg Oncol. 2009; 16:2779–86.

42. Kyo K, Sameshima S, Takahashi M, Furugori T, Sawada T. Impact of autonomic nerve preservation and lateral node dissection on male urogenital function after total mesorectal excision for lower rectal cancer. World J Surg. 2006; 30:1014–9.

43. Sterk P, Shekarriz B, Gunter S, Nolde J, Keller R, Bruch HP, et al. Voiding and sexual dysfunction after deep rectal resection and total mesorectal excision: prospective study on 52 patients. Int J Colorectal Dis. 2005; 20:423–7.

44. Kneist W, Junginger T. Male urogenital function after confirmed nerve-sparing total mesorectal excision with dissection in front of Denonvilliers' fascia. World J Surg. 2007; 31:1321–8.

45. Jayne DG, Brown JM, Thorpe H, Walker J, Quirke P, Guillou PJ. Bladder and sexual function following resection for rectal cancer in a randomized clinical trial of laparoscopic versus open technique. Br J Surg. 2005; 92:1124–32.

46. Kim JY, Kim NK, Lee KY, Hur H, Min BS, Kim JH. A comparative study of voiding and sexual function after total mesorectal excision with autonomic nerve preservation for rectal cancer: laparoscopic versus robotic surgery. Ann Surg Oncol. 2012; 19:2485–93.

47. Park SY, Choi GS, Park JS, Kim HJ, Ryuk JP. Short-term clinical outcome of robot-assisted intersphincteric resection for low rectal cancer: a retrospective comparison with conventional laparoscopy. Surg Endosc. 2013; 27:48–55.

48. Daskalaki D, Aguilera F, Patton K, Giulianotti PC. Fluorescence in robotic surgery. J Surg Oncol. 2015; 112:250–6.

49. Jafari MD, Lee KH, Halabi WJ, Mills SD, Carmichael JC, Stamos MJ, et al. The use of indocyanine green fluorescence to assess anastomotic perfusion during robotic assisted laparoscopic rectal surgery. Surg Endosc. 2013; 27:3003–8.

50. Bae SU, Min BS, Kim NK. Robotic low ligation of the inferior mesenteric artery for rectal cancer using the firefly technique. Yonsei Med J. 2015; 56:1028–35.

51. Chauhan S, Coelho RF, Kalan S, Satava RM, Patel VR. Evolution of robotic surgery: past, present, and future. In : Patel VR, editor. Robotic urologic surgery. 2nd ed. London: Springer-Verlag;2012. p. 3–10.

52. Camarillo DB, Krummel TM, Salisbury JK Jr. Robotic technology in surgery: past, present, and future. Am J Surg. 2004; 188(4A Suppl):2S–15S.

53. Rentschler ME, Dumpert J, Platt SR, Farritor SM, Oleynikov D. Natural orifice surgery with an endoluminal mobile robot. Surg Endosc. 2007; 21:1212–5.

54. Tiwari MM, Reynoso JF, Lehman AC, Tsang AW, Farritor SM, Oleynikov D. In vivo miniature robots for natural orifice surgery: State of the art and future perspectives. World J Gastrointest Surg. 2010; 2:217–23.