Asian Oncol Nurs.  2019 Jun;19(2):90-97. 10.5388/aon.2019.19.2.90.

Menopausal Symptoms and Quality of Life Among Breast Cancer Patients with Chemotherapy-induced Amenorrhea

Affiliations
  • 1College of Nursing · Research Institute of Nursing Science, Ajou University, Suwon, Korea.
  • 2Department of Breast Surgery, School of Medicine, Ajou University, Suwon, Korea.
  • 3College of Nursing, Ajou University, Suwon, Korea. woosoo117@naver.com

Abstract

PURPOSE
The aim of this study was to evaluate the severity of menopausal symptoms and their impact on the quality of life (QOL) in breast cancer patients with chemotherapy-induced amenorrhea.
METHODS
A cross-sectional survey design was used. Participants were 112 breast cancer patients with chemotherapy-induced amenorrhea. They completed the Menopause Rating Scale (MRS) and the Functional Assessment of Cancer Therapy-General (FACT-G). Data were analyzed using descriptive statistics, independent t-tests, one-way ANOVA, Pearson's correlation coefficients, and multiple regression with SPSS/WIN 23.0.
RESULTS
The prevalence of symptoms among the participants were as follows: sleep problems, 88.4%; physical and mental exhaustion, 80.4%; joint and muscular discomfort, 76.8%; and depression, 70.5%. Menopausal symptoms had a significant negative association with QOL. The results of the regression analysis showed that psychological and urogenital symptoms were statistically significant in explaining patients' QOL and accounted for 70% of the total variance.
CONCLUSION
Menopausal symptoms appear to be a significant problem for premenopausal breast cancer patients. Assessment and control of menopausal symptoms played a large role in maintaining the quality of life in breast cancer patients.

Keyword

Breast neoplasms; Menopause; Quality of life; Drug therapy

MeSH Terms

Amenorrhea*
Breast Neoplasms*
Breast*
Cross-Sectional Studies
Depression
Drug Therapy
Female
Humans
Joints
Menopause
Prevalence
Quality of Life*
Full Text Links
  • AON
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
    DB Error: unknown error