Ann Dermatol.  2019 Aug;31(4):463-466. 10.5021/ad.2019.31.4.463.

Therapeutic Effect of 308-nm Excimer Laser on Alopecia Areata in an Animal Model

Affiliations
  • 1Department of Dermatology, Inha University Hospital, Inha University School of Medicine, Incheon, Korea. garden@inha.ac.kr

Abstract

No abstract available.


MeSH Terms

Alopecia Areata*
Alopecia*
Animals*
Lasers, Excimer*
Models, Animal*

Figure

  • Fig. 1 Gross hair regrowth on the control and treated side. Comparison of the baseline (A~D) and the 12 weeks (L~O) shows gross hair regrowth only on the treated side in 3 mice (L~N), but both sides showed similar gross hair regrowth in mouse 3 (O). Red line: cephalocaudal axis, red dotted line: area of alopecia areata.

  • Fig. 2 Histologic appearance in control and treated area through excimer laser therapy. After 3 months of laser therapy, an increase of hair follicle number (A~L: H&E, ×100) and a decrease of CD4+/CD8+ T-cell infiltration (M~T: CD4 stain, CD8 stain, ×400) were detected on the treated side.


Reference

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