Anat Cell Biol.  2017 Jun;50(2):104-106. 10.5115/acb.2017.50.2.104.

The use of human mature cystic ovarian teratoma as a model to study the development of human lymphatics

• Al-Jomard
• Amarin Z

• KMID: 2451235
• DOI: http://doi.org/10.5115/acb.2017.50.2.104

Abstract

The angiogenic theory to the development of human lymphatics is not clear. The objective of this study was to investigate the development of human lymphatics. Semi-thin and thin paraffin sections from human mature cystic ovarian teratoma tissues were studied using light and electron microscopy. Lymphatics were formed by the differentiation of mesenchymal cells that gradually acquired morphological features of endothelial cells. It is suggested that in human mature cystic ovarian teratoma the lymphatic endothelium develops from mesenchymal cells, and not from cells derived from mature endothelium of a preexisting vein or lymphatic.

Keyword

Ovarian teratoma; Human lymphatics; Mesoderm

MeSH Terms

Endothelial Cells
Endothelium
Endothelium, Lymphatic
Humans*
Mesoderm
Microscopy, Electron
Paraffin
Teratoma*
Veins
Paraffin

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