Infect Chemother.  2019 Jun;51(2):188-190. 10.3947/ic.2019.51.2.188.

Validation of the Uniform Case Definition Criteria for Differentiating Tuberculous Meningitis, Viral Meningitis, and Bacterial Meningitis in Adults

• Kim MC
• Park KH
• Lee SA
• Kim SH

• KMID: 2450876
• DOI: http://doi.org/10.3947/ic.2019.51.2.188

Abstract

We validated the uniform case definition for differentiating tuberculous meningitis (TBM) from both viral meningitis (VM) and bacterial meningitis (BM) in adults from South Korea, a country with an intermediate TB-burden. "˜Probable' TBM differentiated "˜definite' TBM with a sensitivity of 81% and specificity of 98%. "˜Possible TBM' criteria identified "˜definite' TBM with a sensitivity of 100% and specificity of 60%. Despite the usefulness of the uniform case definition criteria, there was substantial overlaps among VM, BM, and "˜possible' TBM, especially in severe cases of VM and indolent cases of BM.

Keyword

Tuberculous meningitis; The uniform tuberculous meningitis case definition; Differentiation; Viral meningitis; Bacterial meningitis

MeSH Terms

Adult*
Clothing*
Humans
Korea
Meningitis, Bacterial*
Meningitis, Viral*
Sensitivity and Specificity
Tuberculosis, Meningeal*

Reference

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