Lab Med Online.  2019 Jul;9(3):166-170. 10.3343/lmo.2019.9.3.166.

Mycobacterium shimoidei Pulmonary Disease: The First Case in Korea

• Shin S
• Yoo IY
• Jhun BW
• Koh WJ
• Ki CS
• Lee NY
• Huh HJ

• KMID: 2450842
• DOI: http://doi.org/10.3343/lmo.2019.9.3.166

Abstract

Mycobacterium shimoidei is a nontuberculous mycobacterium (NTM), and is rarely reported as a pathogen causing the NTM pulmonary disease. We describe here the case of a 52-year-old male with symptoms such as chronic cough and a history of pulmonary tuberculosis. Radiologic studies revealed a cavitary lesion in the left upper lobe of his lung. Sputum culture was positive for NTM, which was later identified as M. shimoidei using 16S rRNA and hsp65 sequencing. The patient's symptoms, radiologic evidence, and positive culture results together substantiate that this is the first case of M. shimoidei pulmonary disease from Korea.

Keyword

Nontuberculous mycobacteria; Mycobacterium shimoidei; Lung disease

MeSH Terms

Cough
Humans
Korea*
Lung
Lung Diseases*
Male
Middle Aged
Mycobacterium*
Nontuberculous Mycobacteria
Sputum
Tuberculosis, Pulmonary

Figure

• 

  Fig. 1 Mycobacterium shimoidei pulmonary disease in a 52-year-old male patient. Chest high-resolution computed tomography shows a thick-walled cavity in the left upper lobe of the lung. Note the associated emphysema in the left upper lobe, which suggests the sequelae of previous pulmonary tuberculosis.

• 

  Fig. 2 Neighbor-joining phylogenetic tree showing the relationships of Mycobacterium shimoidei and other Mycobacterium species (A, 16S rDNA; B, hsp65 gene). Reference sequences are from species type strains; GenBank accession numbers are given in parentheses.

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