Korean J Blood Transfus.  1994 Nov;5(2):151-158.

A Case of Hernolytio Disease of the Newborn due to Anti-Dib Antibody

• Kim HC
• Kang MJ
• Chae JH
• Shim WS
• Nahm CH
• Hah KS

Abstract

The Di(a+b-) phenotype is extremely rare among Caucaclans and mostly confined to mongoloids. The incidences of Di antigen among Koreans were reported to be 6.1 to 14.5%, with an average of 9.6%; it can be calculated that the frequency of Di(a+b-) is 0.25% on the average. Authors report the first case of hemolytic disease of the newborn due to anti-Dib in Korea. The Diego phenotypes of the mother, baby and father were Di(a+b-), Di(a+b+) and Di (a-b+), respectively. The mother's serum and eluate from infant's erythrocytes contained anti-DP antibody active in the antiglobulin phase. After transfusions of Di-negative red cells from the mother and mother's relative, the patient was recovered from anemia and jaundice.

MeSH Terms

Anemia
Erythrocytes
Fathers
Humans
Incidence
Infant, Newborn*
Jaundice
Korea
Mothers
Phenotype