Korean J Pediatr Hematol Oncol.  1999 Apr;6(1):131-135.

A Case of Hemolytic Disease of the Newborn in Identical Twin due to Anti-c antibody

• Yoo CH
• Cho HS
• Min KS
• Kim JW
• Park CY
• Ryoo KY

Abstract

Anti-c is an important Rh antibody that causes hemolytic disease of the newborn. Recently we had a case of hemolytic disease of the newborn in identical twin due to anti-c. The five-day-old female twin were admitted at our hospital due to jaundice. There were no ABO and Rh (D) incompatibilities between mother and babies. The newborn's direct and indirect antiglobulin tests were positive and the maternal serum showed a positive antibody screening test. The laboratory findings warranted hemolytic disease of newborn due to other Rh antibodies. The specificity of unexpected antibodies were anti-c in maternal serum and fetal serums. The babies were treated with only phototherapy for 10 days and discharged in recovery.

Keyword

Anti-c; Hemolytic disease of newborn

MeSH Terms

Antibodies
Coombs Test
Erythroblastosis, Fetal
Female
Humans
Infant, Newborn*
Jaundice
Mass Screening
Mothers
Phototherapy
Sensitivity and Specificity
Twins, Monozygotic*
Antibodies