Korean J Pancreas Biliary Tract.
2015 Apr;20(2):78-82. 10.15279/kpba.2015.20.2.78.
A Case of Pancreatic Cancer with Markedly Elevated Serum Immunoglobulin G4
- Affiliations
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- 1Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea. endomoon@naver.com
- KMID: 2448478
- DOI: http://doi.org/10.15279/kpba.2015.20.2.78
Abstract
- Differential diagnosis between autoimmune pancreatitis (AIP) and pancreatic cancer is often difficult due to similar clinical manifestations and radiological findings. Serum immunoglobulin G4 (IgG4) is a marker to differentiate AIP from pancreatic cancer. Although serum IgG4 can be elevated in 10% of patients with pancreatic cancer, most of serum IgG4 elevation in pancreatic cancer is limited within two times of upper normal limit. Herein, we report a case of pancreatic cancer with markedly elevated serum IgG4 over six times of upper normal limit that needed steroid trial to differentiate from AIP.
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