Nucl Med Mol Imaging.  2019 Apr;53(2):148-151. 10.1007/s13139-018-00568-5.

Tracer Accumulation in Relation to Venous Thrombus on ¹⁸F-DOPA PET/CT in a Case of Persistent Hyperinsulinemic Hypoglycemia of Infancy

• Arora S
• Damle NA
• Passah A
• Sharma R
• Goyal H
• Arunraj ST
• Gupta P
• Jana M

• KMID: 2448103
• DOI: http://doi.org/10.1007/s13139-018-00568-5

Abstract

¹â¸F-DOPA PET/CT is commonly done in patients with persistent hyperinsulinemic hypoglycemia of infancy (PHHI) to look for any focal lesion in the pancreas.We present the findings in a 20-day-old neonate with PHHI who underwent ¹â¸F-DOPA PET/CT. The scan showed diffuse uptake in the pancreas with no focal lesion, physiologic excretion into the genito-urinary system, and interestingly tracer accumulation was seen in the inferior vena cava and ilio-femoral veins which is a non-physiological site for tracer accumulation. The uptake corresponded to a large venous thrombus which was confirmed by a venous Doppler.

Keyword

Venous thrombus; ¹⁸F-DOPA PET/CT; Persistent hyperinsulinemic hypoglycemia of infancy (PHHI); Congenital hyperinsulinism

MeSH Terms

Congenital Hyperinsulinism*
Humans
Infant, Newborn
Pancreas
Positron-Emission Tomography and Computed Tomography*
Thrombosis*
Veins
Vena Cava, Inferior