J Korean Orthop Assoc.  1984 Oct;19(5):983-986. 10.4055/jkoa.1984.19.5.983.

Malignant Schwannoma: Report of Two Cases

Abstract

A Malignant Schwannoma is a relatively rare primary nerve sheath tumor arises from Sehwann cells of the peripheral nerves. This tumor is frequently associated with von Recklinghausens disease. A high percentage of patients experience local recurrence even after radical surgical excision, and eventual pulmonary metastases via the intraneural and hematogenous routes. The treatment of choice is radical excision or amputation. Results of treatment with radiation and chemotherapy have been disappointing. The authors have experienced two cases of Malignant Schwannoma, one of which was located in the median nerve of the palm, the other in the ulnar nerve of the arm, but neither were associated with von Recklinghausens disease.

Keyword

Malignant Schwannoma; Treatment

MeSH Terms

Amputation
Arm
Drug Therapy
Humans
Median Nerve
Neoplasm Metastasis
Neurilemmoma*
Neurofibromatosis 1
Peripheral Nerves
Recurrence
Ulnar Nerve
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