Ann Dermatol.  1991 Jul;3(2):119-125. 10.5021/ad.1991.3.2.119.

Two Cases of Malignant Schwannoma in Association with Neurofibromatosis

• Kim SJ
• Yi JU
• Ro YS
• Park CK
• Kim JH

• KMID: 2362003
• DOI: http://doi.org/10.5021/ad.1991.3.2.119

Abstract

We report two cases of malignant schwannoma of skin in association with non-familial neurofibromatosis. Case 1, a 47 year old man, had a large subcutaneous tumor on the sacral area and case 2, a 62 year old woman, a painful, ulcerating tumor on the posterior aspect of the left arm. Both cases were histopathologically confirmed as malignant schwannomas and immunohistochemical studies showed 5-100 protein in the tumor cells. After surgical excision of the tumors, case 1 was lost to follow up, while case 2 remained without evidence of disease for more than one and half years.

Keyword

Malignant schwannoma; Neurofibromatosis

MeSH Terms

Arm
Female
Humans
Lost to Follow-Up
Neurilemmoma*
Neurofibromatoses*
Skin
Ulcer