Korean J Ophthalmol.  2019 Apr;33(2):202-203. 10.3341/kjo.2018.0074.

Rare Case of Nerve Sheath Myxoma of the Eyelid Misdiagnosed as Mucocele

Affiliations
  • 1Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
  • 2Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 3Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea. resourceful@hanmail.net

Abstract

No abstract available.


MeSH Terms

Eyelids*
Mucocele*
Neurothekeoma*

Figure

  • Fig. 1 (A) Photograph of the patient's eye at the time of his first visit. A mass (black arrow) at the medial canthus with drooped eyelid skin is observed. (B) Orbit computed tomography image shows an ill-defined enhancing soft tissue lesion (white arrow) at the medial canthal area of the right orbit. (C) Photograph of the patient's eye after complete excision of nerve sheath myxoma. The mass at the medial canthus and drooped eyelid skin had disappeared (black arrow). (D) Histopathologic analysis revealed epithelioid and stellate neoplastic Schwann cells (black arrow) with an abundant myxoid matrix (H&E, ×400). (E) Immunohistochemical staining for S-100 showed a strong positivity (S-100, ×200). Written informed consent from the patient was obtained.


Reference

1. Harkin JC, Reed RJ. Tumors of the peripheral nervous system. Washington, DC: Armed Forces Institute of Pathology;1969. p. 60–64.
2. Kakizaki H, Zako M, Iwaki M, Mito H. Successful percutaneous incision and pathological examination of a rare nerve sheath myxoma: diagnosis and treatment. Jpn J Ophthalmol. 2004; 48:78–79.
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3. Papalas JA, Proia AD, Hitchcock M, et al. Neurothekeoma palpebrae: a report of 3 cases. Am J Dermatopathol. 2010; 32:374–379.
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4. Fetsch JF, Laskin WB, Miettinen M. Nerve sheath myxoma: a clinicopathologic and immunohistochemical analysis of 57 morphologically distinctive, S-100 protein- and GFAP-positive, myxoid peripheral nerve sheath tumors with a predilection for the extremities and a high local recurrence rate. Am J Surg Pathol. 2005; 29:1615–1624.
5. Fetsch JF, Laskin WB, Hallman JR, et al. Neurothekeoma: an analysis of 178 tumors with detailed immunohistochemical data and long-term patient follow-up information. Am J Surg Pathol. 2007; 31:1103–1114.
Article
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