J Korean Med Sci.  1992 Mar;7(1):85-89. 10.3346/jkms.1992.7.1.85.

Nerve sheath myxoma (neurothekeoma): a case report

Affiliations
  • 1Department of Pathology, College of Medicine, Inje University Seoul Paik Hospital, Korea.

Abstract

A case of nerve sheath myxoma also called as neurothekeoma in a 33-year-old woman is described. The lesion appeared as a painful, elevated nodule on the scalp for several months, without an appreciable increase in size. Microscopically, it showed typical histologic characteristics of nerve sheath myxoma, and tumor cells revealed strong, positive reaction for S-100 protein and negativity for epithelial membrane antigen (EMA) on immunohistochemical staining. These immunohistochemical findings of this case support the view that the origin cells of this tumor may be schwann cells rather than perineurial cells. The histogenesis and differential diagnosis of this tumor are discussed.

Keyword

Myxoma; Nerve sheath tumor; Neurothekeoma; S-100 protein; EMA; Myxoid neurofibroma

MeSH Terms

Adult
Diagnosis, Differential
Female
Humans
Myelin Sheath/*pathology
Myxoma/*pathology
*Scalp
Skin Neoplasms/*pathology
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