Clin Pain.  2018 Dec;17(2):107-110. 10.0000/cp.2018.17.2.107.

The Effect of Cervical Stellate Ganglion Block Using Botulinum Toxin Type A in Intractable Cancer-related Pain: Case Report

• Sohn D
• Park GY
• Im S
• Jeon SH
• Choi Y

• KMID: 2439568
• DOI: http://doi.org/10.0000/cp.2018.17.2.107

Abstract

OBJECTIVE
For patients who do not relieve with pharmacological intervention, interventional treatment including neurolytic blocks may have a specific role in palliative cancer management. METHOD: We performed cervical stellate ganglion block for the second time with Botulinum toxin type A mixed with 4 ml of normal saline, total 75 IU of Botulinum toxin type A, minimal effective dosage was measured to minimize the possible side effects.
RESULTS
About 3 days later, the patient reported that her continuous pain intensity had decreased from 8/10 to 4/10 on the visual analogue scale score. The frequency of the pain attack that required additional morphine injections was also decreased. As a result, her maximum morphine requirement dose per day was significantly reduced.
CONCLUSION
In this case, cervical stellate ganglion block with Botulinum toxin had longer lasting effect in the continuous pain intensity and resulted in less frequent pain attack. Botulinum toxin can be a possible intervention material in intractable neuropathic pain related to cancer.

Keyword

Cancer pain; Botulinum toxin; Cervical stellate ganglionic block

MeSH Terms

Botulinum Toxins*
Botulinum Toxins, Type A*
Humans
Methods
Morphine
Neuralgia
Stellate Ganglion*
Botulinum Toxins
Botulinum Toxins, Type A
Morphine