J Breast Cancer.  2017 Sep;20(3):314-318. 10.4048/jbc.2017.20.3.314.

Invasive Micropapillary Carcinoma in Axillary Ectopic Breast and Synchronous Ductal Carcinoma In Situ in the Contralateral Breast

Affiliations
  • 1Department of Radiology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea. nico1220@dreamwiz.com
  • 2Department of Pathology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea.
  • 3Department of Surgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea.

Abstract

The development of ectopic breast tissue is attributable to the failure of primitive mammary tissue to regress after the development of the mammary ridge, except at pectoral breast sites, and is most often evident in the axillae. Several benign and malignant breast diseases have been reported in ectopic axillary breast tissues. The most common cancerous pathology of ectopic breast tissue is invasive ductal carcinoma. Ectopic breast cancer presenting with simultaneous primary cancer of the pectoral breast is extremely rare. Herein, we report an invasive micropapillary carcinoma of an axillary ectopic breast, combined with a synchronous ductal carcinoma in situ in the contralateral pectoral breast of a 61-year-old woman.

Keyword

Axilla; Breast neoplasms; Choristoma

MeSH Terms

Axilla
Breast Diseases
Breast Neoplasms
Breast*
Carcinoma, Ductal*
Carcinoma, Intraductal, Noninfiltrating*
Choristoma
Female
Humans
Middle Aged
Pathology

Figure

  • Figure 1 Mammographic findings of invasive micropapillary carcinoma in axillary ectopic breast. (A) Mediolateral oblique view of mammogram shows focal asymmetry with microcalcifications (arrow) in the right axilla. (B) Axillary fibroglandular tissue with the same radiological appearance as normal breast tissue (arrowheads) is also seen in the left axilla. (C) Zoomed mediolateral oblique view of right mammogram shows focal asymmetry and mass with microcalcifications (arrows) in the axilla.

  • Figure 2 Mammographic findings of left breast. Magnified craniocaudal view of mammogram shows grouped, fine pleomorphic microcalcifications (arrows) in the upper outer quadrant of the left breast.

  • Figure 3 Sonographic findings of invasive micropapillary carcinoma in axillary ectopic breast. (A) Ultrasound image obtained in a local breast clinic shows several, irregular hypoechoic masses in the right axilla. (B) Echogenic area with the same appearance as that of normal breast tissue compatible with ectopic breast (arrowheads) is seen around the masses.

  • Figure 4 Histopathological findings. (A) Invasive micropapillary carcinoma and micropapillary ductal carcinoma in situ (arrows) are seen within the fatty mammary stroma with mammary lobules (arrowheads) in the right axilla (H&E stain, ×20). (B) Ductal carcinoma in situ with central necrosis and calcifications is seen in the left breast (H&E stain, ×200).


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