J Audiol Otol.  2019 Jan;23(1):15-19. 10.7874/jao.2018.00276.

Single Dose Topical Application of Clotrimazole for the Treatment of Otomycosis: Is This Enough?

Affiliations
  • 1Department of Otorhinolaryngology, Vocational School of Health Scienses, Acıbadem Mehmet Ali Aydınlar University, Eskis¸ ehir Hospital, Eskis¸ ehir, Turkey. dundarkbb2@gmail.com
  • 2Department of Otorhinolaryngology, Harran University, S¸ anlıurfa, Turkey.

Abstract

BACKGROUND AND OBJECTIVES
To determine the efficacy of filling the external auditory meatus with 1% clotrimazole at a single visit for the treatment of otomycosis.
SUBJECTS AND METHODS
This prospective study included 40 patients who were referred to our clinic with complaints of ear itching, pain, and fullness, and were diagnosed with unilateral otomycosis. After cleaning the mycotic hyphae from the external auditory meatus, the ear canal was filled with 1% clotrimazole, using an intravenous catheter and syringe. The patients received follow-up examinations on post-treatment days 7, 15, and 45.
RESULTS
The follow-up otomicroscopic examinations revealed that 95% of the ear canals were entirely clean and that all symptoms had resolved. The post-treatment scores of pain, aural fullness and itching were significantly lower than the pre-treatment scores (p < 0.01).
CONCLUSIONS
Filling the external auditory meatus with 1% clotrimazole at a single visit is an easy, efficient, and cost-effective treatment for otomycosis. Additionally, high patient compliance makes this treatment superior to long-term topical therapy.

Keyword

Otomycosis; Topical treatment; Clotrimazole

MeSH Terms

Catheters
Clotrimazole*
Ear
Ear Canal
Follow-Up Studies
Humans
Hyphae
Otomycosis*
Patient Compliance
Prospective Studies
Pruritus
Syringes
Clotrimazole
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