Korean J Dermatol.  2018 Jul;56(6):389-392.

Two Cases of Postoperative Pyoderma Gangrenosum

Affiliations
  • 1Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. miumiu@amc.seoul.kr

Abstract

Pyoderma gangrenosum (PG) is an uncommon ulcerating inflammatory neutrophilic dermatosis. Multifactorial pathogenesis has been reported because the underlying mechanism needs to be clearly elucidated. A pathergic reaction is a pathogenic aggravating factor of PG. The occurrence of postoperative PG (PPG) within and involving the borders of a surgical incision site suggests the role of a pathergic reaction in PG. Massive debridement should be avoided in PPG, and it should be immediately managed with oral prednisolone. We present 2 cases of PPG with different clinical courses according to the primary management.

Keyword

Cytokines; Pyoderma gangrenosum; Postoperative pyoderma gangrenosum; Skin

MeSH Terms

Cytokines
Debridement
Neutrophils
Prednisolone
Pyoderma Gangrenosum*
Pyoderma*
Skin
Skin Diseases
Ulcer
Cytokines
Prednisolone
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