Korean J Otorhinolaryngol-Head Neck Surg.  2018 Oct;61(10):557-560. 10.3342/kjorl-hns.2017.00969.

A Case of 18-Year-Old Female with Nasopharyngeal Diffuse Large B Cell Lymphoma

• Lee WW
• Song Y
• Seong J
• Kim HJ

• KMID: 2436549
• DOI: http://doi.org/10.3342/kjorl-hns.2017.00969

Abstract

Malignant lymphoma is tumor of the immune system. It is mainly found in the lymph node but it can also originate from extranodal organs such as gastrointestinal tract, sinonasal tract, and etc. We experienced a case of 18-year-old female patient with a huge nasopharyngeal mass. The patient visited our clinic with complaints of nasal obstruction and mouth breathing without general symptoms. After extirpation and biopsy of the nasopharyngeal mass, lesion was diagnosed as malignant lymphoma. In immunohistochemistry, CD 20, Bcl-2, Bcl-6 were positive. Final diagnosis was diffused large B cell lymphoma, for which she received chemotherapy (Rituximab, Cyclophosp, Ahamide, Adriamycin, Vincristine, Prednisone). We report a case of huge malignant lymphoma that occurred in the nasopharynx with a brief review of literature.

Keyword

Chemotherapy; Diffuse large B cell lymphoma; Lymphoma; Nasopharynx Therapeutic

MeSH Terms

Adolescent*
Biopsy
Diagnosis
Doxorubicin
Drug Therapy
Female*
Gastrointestinal Tract
Humans
Immune System
Immunohistochemistry
Lymph Nodes
Lymphoma
Lymphoma, B-Cell*
Mouth Breathing
Nasal Obstruction
Nasopharynx
Vincristine
Doxorubicin
Vincristine