Korean J Otorhinolaryngol-Head Neck Surg.  2018 May;61(5):242-246. 10.3342/kjorl-hns.2017.00521.

Hearing Outcomes and Prognostic Factors in Idiopathic Sudden Sensorineural Hearing Loss Patients with Combined Intratympanic and Systemic Steroid Therapy

• Baek MK
• Cho CH
• Bang YJ
• Oh NR
• Baek MJ
• Lee JH

• KMID: 2436462
• DOI: http://doi.org/10.3342/kjorl-hns.2017.00521

Abstract

BACKGROUND AND OBJECTIVES
Hearing outcomes and prognostic factors of idiopathic sudden sensorineural hearing loss (SSNHL) were investigated in patients who underwent combined intratympanic and systemic steroid therapy.
SUBJECTS AND METHOD
This study was performed by retrospective chart review. Clinical outcomes and prognostic factors were evaluated in 147 patients who received intratympanic steroid plus systemic steroid therapy.
RESULTS
Complete hearing recovery was achieved in 36.7% (n=54) of the patients, partial recovery in 12.9% (n=19), slight recovery in 12.3% (n=18), and total recovery in 61.9% (n=91). Age was identified as an independent, negative prognostic factor for hearing recovery. The recovery rates of the down sloping and profound types were poorer than those of the up sloping type as determined by audiography.
CONCLUSION
The results of this study suggest that the combined treatment of intratympanic and systemic steroids for idiopathic SSNHL results in high hearing recovery rates, and that the down-sloping and profound types of audiogram patterns and age are negative prognostic factors.

Keyword

Hearing loss; Middle ear; Prognosis; Steroid; Sudden

MeSH Terms

Ear, Middle
Hearing Loss
Hearing Loss, Sensorineural*
Hearing*
Humans
Methods
Prognosis
Retrospective Studies
Steroids
Steroids