J Korean Neurol Assoc.  2018 Nov;36(4):350-353. 10.17340/jkna.2018.4.16.

Ischemic Stroke with Cerebral Vasculopathy in POEMS Syndrome

Affiliations
  • 1Department of Neurology, Severance Hospital, Yonsei University of College of Medicine, Seoul, Korea. neuro05@yuhs.ac
  • 2Department of Radiology, Severance Hospital, Yonsei University of College of Medicine, Seoul, Korea.

Abstract

Ischemic stroke caused by the cerebral vasculopathy is a rare complication of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome. We present a case of recurrent ischemic strokes caused by cerebral vasculopathy in a patient with POEMS syndrome. A 34-year-old man presented with gait disturbance and dizziness. Brain magnetic resonance imaging demonstrated acute ischemic stroke in the middle cerebral artery-anterior cerebral artery (MCA-ACA) border zones of bilateral hemispheres. Repeated angiographic studies showed progressive worsening of the left distal internal carotid artery, ACA, and MCA stenoses, along with sustained steno-occlusion of right MCA.

Keyword

POEMS syndrome; Vascular disease; Stroke

MeSH Terms

Adult
Brain
Carotid Artery, Internal
Cerebral Arteries
Constriction, Pathologic
Dizziness
Gait
Humans
Magnetic Resonance Imaging
Paraproteinemias
POEMS Syndrome*
Polyneuropathies
Skin
Stroke*
Vascular Diseases
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