J Korean Neurol Assoc.  2018 Nov;36(4):318-321. 10.17340/jkna.2018.4.8.

Small Fiber Neuropathy and Postural Orthostatic Tachycardia Syndrome after Human Papillomavirus Vaccination

Affiliations
  • 1Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. kkkim@amc.seoul.kr

Abstract

We describe a 44-year-old woman with paresthesia, fatigue, and palpitation, 10 days after human papillomavirus (HPV) vaccination. The quantitative sensory test showed abnormal detection threshold in her foot. Tilt test result indicated postural orthostatic tachycardia syndrome. Symptoms were improved after immunomodulating therapy, pain control drug, and oral beta blocker medication. This is first case report for small fiber neuropathy and autonomic dysfunction after HPV vaccination in Korea.

Keyword

Papillomavirus vaccines; Small fiber neuropathy; Postural orthostatic tachycardia syndrome

MeSH Terms

Adult
Erythromelalgia*
Fatigue
Female
Foot
Humans*
Korea
Papillomavirus Vaccines
Paresthesia
Postural Orthostatic Tachycardia Syndrome*
Vaccination*
Papillomavirus Vaccines
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