Korean J Hosp Palliat Care.  2018 Dec;21(4):152-157. 10.14475/kjhpc.2018.21.4.152.

Successful Treatment with Transdermal Buprenorphine Patch in Opioid-Dependent Cancer Patients: Case Series

• Go SI
• Kim JH
• Lee GW
• Kang JH

• KMID: 2435587
• DOI: http://doi.org/10.14475/kjhpc.2018.21.4.152

Abstract

Opioid aberrant behavior is an emerging problem as strong opioid is increasingly used to alleviate cancer pain in patients with cancer. Although the treatment of opioid addiction and physical dependence for non-cancer pain is well known, few studies have been conducted with cancer patients, particularly in the Korean population. Presented here are ten cases of cancer patients who were physically dependent on strong opioid and successfully treated with a partial mu-opioid receptor agonist, buprenorphine. This is the first report showing the efficacy of transdermal buprenorphine as a treatment for physical dependence on opioid medication in cancer patients.

Keyword

Opioid analgesics; Cancer pain; Opioid-related disorders; Buprenorphine

MeSH Terms

Analgesics, Opioid
Buprenorphine*
Humans
Opioid-Related Disorders
Analgesics, Opioid
Buprenorphine