J Korean Child Neurol Soc.  2018 Mar;26(1):66-69. 10.26815/jkcns.2018.26.1.66.

Concurrence of Diabetic Ketoacidosis and Acute Ischemic Stroke due to Moyamoya Disease

• Lee H
• Lee J
• Kim S
• Oh MS
• Han KH
• Kang KS
• Kim S

• KMID: 2435278
• DOI: http://doi.org/10.26815/jkcns.2018.26.1.66

Abstract

Although the etiology of moyamoya disease (MMD) remains unknown, autoimmunity is one of the proposed pathogeneses. Unlike other autoimmune disorders that are associated with cerebral arteritis, concurrence of MMD and diabetes mellitus (DM) is rare. However, we encountered a patient with concurrent diabetic ketoacidosis (DKA) and acute ischemic stroke due to MMD. Our patient was diagnosed with glutamic acid decarboxylase antibody-positive type 2 DM (T2DM) based on laboratory and physical examination findings. Brain magnetic resonance images revealed an acute ischemic stroke in the left cerebral hemisphere and bilateral diffuse stenosis/occlusion in the middle cerebral artery and multiple collaterals. Thus, here, we report a patient with both T2DM and MMD who developed an acute ischemic stroke that was complicated by DKA.

Keyword

Diabetic ketoacidosis; Type 2 diabetes mellitus; Moyamoya disease

MeSH Terms

Arteritis
Autoimmunity
Brain
Cerebrum
Diabetes Mellitus
Diabetes Mellitus, Type 2
Diabetic Ketoacidosis*
Glutamate Decarboxylase
Humans
Middle Cerebral Artery
Moyamoya Disease*
Physical Examination
Stroke*
Glutamate Decarboxylase