Biomed Eng Lett.
2018 Aug;8(3):267-272. 10.1007/s13534-018-0065-4.
Mechanical properties and cytotoxicity of PLA/PCL films
- Affiliations
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- 1Convergence Institute of Biomedical Engineering and Biomaterials, Seoul National University of Science and Technology, Seoul 01811, Korea.
- 2Department of Biomedical Engineering, Daelim University, Anyang 13916, Korea. dylee@daelim.ac.kr
- 3Department of Mechanical Engineering, University of Nevada, Las Vegas, NV 89154, USA.
- KMID: 2434894
- DOI: http://doi.org/10.1007/s13534-018-0065-4
Abstract
- Thermodynamically immiscible poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL) were blended and solution-cast by adding the 3% compatibilizer (tributyl citrate, TBC) of the PCL weight. In the PLA/PCL composition range of 99/1-95/5 wt%, mechanical properties of the PLA/PCL films with TBC were always superior to those of the films without TBC. The tensile strength of 42.9 ± 3.5 MPa and the elongation at break of 10.3 ± 2.7% were observed for the 93/7 PLA/PCL films without TBC, indicating that PCL addition is effective for strength and ductility. However, the tensile strength of 54.1 ± 3.4 MPa and the elongation at break of 8.8 ± 1.8% were found for the 95/5 PLA/PCL with TBC, indicating that the effect of co-addition of PCL and TBC on mechanical properties of the films is more pronounced. No cytotoxicity was observed for the PLA/PCL films regardless of TBC addition.
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