Mood Emot.  2018 Nov;16(3):123-128. 10.0000/me.2018.16.3.123.

Korean Medication Algorithm for Bipolar Disorder 2018 : The Elderly

Affiliations
  • 1Department of Psychiatry, School of Medicine, Jeju National University, Jeju, Korea.
  • 2Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea. wmbahk@catholic.ac.kr
  • 3Department of Psychiatry, Naju National Hospital, Naju, Korea.
  • 4Department of Psychiatry, Sacred Heart Hospital, Hallym University, Anyang, Korea. cogni@naver.com
  • 5Department of Psychiatry, School of Medicine, Konkuk University, Chungju, Korea.
  • 6Department of Psychiatry, Seoul Paik Hospital, College of Medicine, Inje University, Seoul, Korea.
  • 7Department of Psychiatry, Haeundae Paik Hospital, College of Medicine, Inje University and Paik Institute for Clinical Research, Busan, Korea.
  • 8Department of Health Science and Technology, Graduate School of Inje University, Busan, Korea.
  • 9Department of Psychiatry, Keyo Hospital, Keyo Medical Foundation, Uiwang, Korea.
  • 10Department of Psychiatry, Soonchunhyang University Cheonan Hospital, Soonchunhyang University, Cheonan, Korea.
  • 11Department of Psychiatry, Myongji Hospital, Goyang, Korea.
  • 12Department of Psychiatry, College of Medicine, Chung-Ang University, Seoul, Korea.

Abstract


OBJECTIVES
The fourth revision of Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP) was performed to provide more proper guidelines for clinicians. In this study, we evaluated treatment strategies of elderly patients with bipolar disorders of KMAP-BP 2018.
METHODS
Sixty-one psychiatrists of the review committee with vast clinical experiences in treating bipolar disorders, completed the survey. An expert consensus was obtained, on pharmacological treatment strategies for elderly patients with bipolar disorder. The executive committee analyzed results, and discussed the results to produce the final algorithm.
RESULTS
In elderly patients with bipolar disorder, first-line treatment option for acute manic episode is monotherapy, with atypical antipsychotics or mood stabilizer, and a combination of mood stabilizer and atypical antipsychotics. First-line treatment option for acute depressive episode, was a combination of mood stabilizer and atypical antipsychotics, monotherapy with atypical antipsychotic or mood stabilizer, and atypical antipsychotics with lamotrigine.
CONCLUSION
In KMAP-BP 2018, the recommendation for treatment option in elderly patients with bipolar disorder, was newly introduced. We expect this algorithm may provide valuable information, and facilitate treatment of elderly patients with bipolar disorder.

Keyword

Bipolar disorder; Elderly; Pharmacotherapy; KMAP-BP 2018

MeSH Terms

Advisory Committees
Aged*
Antipsychotic Agents
Bipolar Disorder*
Consensus
Drug Therapy
Humans
Psychiatry
Antipsychotic Agents
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