Kosin Med J.  2018 Dec;33(2):228-234. 10.7180/kmj.2018.33.2.228.

A Case of Ceruminous Adenoma Arising from the External Auditory Canal

• Yeo SC
• Lee HJ
• Kim JY
• Kim DW
• Seo JH
• Ahn SK

• KMID: 2430739
• DOI: http://doi.org/10.7180/kmj.2018.33.2.228

Abstract

Ceruminous adenoma is a benign neoplasm of the ceruminous gland, and its development in human external auditory canal is very rare. Due to the limited number of cases, controversy still exists about nomenclature, classification, diagnosis and its treatment. Recently we experienced a 55 years old woman who was diagnosed with ceruminous adenoma of the external auditory canal, and who was treated with wide excision. So we report this uncommon case in combination with a review of the literature.

Keyword

Adenoma; Ceruminous gland; External auditory canal

MeSH Terms

Adenoma*
Classification
Diagnosis
Ear Canal*
Female
Humans

Figure

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  Fig. 1 Mass arising from antero-superior portion of right external auditory canal with smooth surface was noted.

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  Fig. 2 Enhanced axial (A) and coronal (B) temporal bone CT scan shows an about 1.1cm size non-enhancing heterogeneous mass lesion (arrow) with adjacent bony erosion (astrix).

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  Fig. 3 Dissected yellowish mass with piecemeal technique. The diameter of the largest one was about 0.6cm.

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  Fig. 4 A microscopic view shows the biphasic nature of the main mass. The inner apocrine cells have a eosinophilic cytoplasm (arrow), subtended by small myoepithelial cells (dotted line arrow). (H&E, ×200)

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  Fig. 5 Positive immunohistochemical staining for CK 7 (A) and p63 (B). ( ×200)

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  Fig. 6 Endoscopic finding of post-operation 10 month; the mass located on the antero-superior portion of right external auditory canal was completely removed and there is no evidence of recurrence.

Reference

1. Elsürer C, Senkal HA, Baydar DE, Sennaroğlu L. Ceruminous adenoma mimicking furunculosis in the external auditory canal. Eur Arch Otorhinolaryngol. 2007; 264:223–225.

2. Psillas G, Krommydas A, Karayannopoulou G, Chatzopoulos K, Kanitakis J, Markou K. Ceruminous Adenoma of the External Auditory Canal: A Case Report with Imaging and Pathologic Findings. Case Rep Med. 2015; 2015:359627.

3. Shen WQ, Cheng KJ, Bao YY, Zhou SH, Yao HT. Expression of Glut-1, HIF-1a, PI3K and p-Akt in a case of ceruminous adenoma. Head Neck Oncol. 2012; 4:18.

4. Kim SW, Choi JH. Ceruminous Adenoma Mimicking Otofuruncle in the External Auditory Canal. Korean J Otorhinolaryngol-Head Neck Surg. 2011; 54:501–503.

5. Kim SC, Lee HK, Ahn SY, Lee JH. Two Cases of Ceruminous Adenoma Arising from the External Auditory Canal. Korean J Otolaryngol-Head Neck Surg. 1997; 40:1059–1062.

6. Lee KY. Ceruminoma of the External Auditory Canal. Korean J Otolaryngol-Head Neck Surg. 1982; 25:543–546.

7. Cho HY, Hwang HY, Han KC, Kim NR. Ceruminous Adenoma of the External Auditory Canal - Report of Two Cases. Korean J Head Neck Oncol. 2009; 25:146–149.

8. Spielmann PM, McKean S, White RD, Hussain SS. Surgical management of external auditory canal lesions. J Laryngol Otol. 2013; 127:246–251.

9. Elsürer C, Senkal HA, Baydar DE, Sennaroğlu L. Ceruminous adenoma mimicking furunculosis in the external auditory canal. Eur Arch Otorhinolaryngol. 2007; 264:223–225.

10. Mills RG, Douglas-Jones T, Williams RG. ‘Ceruminoma’--a defunct diagnosis. J Laryngol Otol. 1995; 109:180–188.

11. Magliulo G, Bertin S. Adenoma of the ceruminous gland. Otolaryngol Head Neck Surg. 2010; 143:459–460.

12. Niemczyk E, Niemczyk K, Maldyk J, Zawadzka-Glos L. Ceruminous adenoma (ceruminoma) arising in a nevus sebaceus of Jadassohn within the external auditory canal of a 3 year-old boy - A case report. Int J Pediatr Otorhinolaryngol. 2015; 79:1932–1934.

13. Thompson LD, Nelson BL, Barnes EL. Ceruminous adenomas: a clinicopathologic study of 41 cases with a review of the literature. Am J Surg Pathol. 2004; 28:308–318.