Ann Dermatol.  2016 Feb;28(1):140-141. 10.5021/ad.2016.28.1.140.

Single Vesicular Papule on the Eyelid with Atypical Histopathology Findings

• Hyun MY
• Seok J
• Park KY
• Kim BJ
• Seo SJ
• Hong CK

• KMID: 2429505
• DOI: http://doi.org/10.5021/ad.2016.28.1.140

Abstract

No abstract available.

MeSH Terms

Eyelids*

Figure

• 

  Fig. 1 Skin findings of the present case. Single, 0.2×0.2 cm, well-demarcated, yellowish, pedunculated vesicular papule on the left upper eyelid.

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  Fig. 2 Histopathologic findings of present case. (A) A well-circumscribed, oval shaped, cribriform intradermal tumor was observed without connection to the epidermis (H&E, ×40). (B) The tumor cells were cuboidal with eosinophilic cytoplasm, and decapitation secretion was observed (H&E, ×200). (C) Tumor cells did not show definite cytologic atypia or an outer myoepithelial layer (H&E, ×200). (D) Immunohistochemical stain for cytokeratin (CK) 7 was positive and (E) CK20 was weakly positive (D, E: ×100).

Reference

1. Hunold AC, Herwig MC, Holz FG, Fischer HP, Loeffler KU. Pigmented tumour of the eyelid with unexpected findings. Case Rep Pathol. 2012; 2012:471368.

2. Figueira EC, Danks J, Watanabe A, Khong JJ, Ong L, Selva D. Apocrine adenocarcinoma of the eyelid: case series and review. Ophthal Plast Reconstr Surg. 2013; 29:417–423.

3. Hollowell KL, Agle SC, Zervos EE, Fitzgerald TL. Cutaneous apocrine adenocarcinoma: defining epidemiology, outcomes, and optimal therapy for a rare neoplasm. J Surg Oncol. 2012; 105:415–419.

4. Akcay EK, Simsek S, Cagil N, Belenli O, Gumus M. Apocrine adenocarcinoma of the right eyelid and apocrine adenoma of the left maxillary sinus. Can J Ophthalmol. 2008; 43:609–610.

5. Valenzuela AA, Cupp DG, Heathcote JG. Primary apocrine adenocarcinoma of the eyelid. Orbit. 2012; 31:316–318.