J Korean Assoc Pediatr Surg.  2001 Jun;7(1):68-72.

Spnontaneous Regrssion of liver metastasis in Stage IV-S neuroblastoma after adrenalectomy: One Case Report

• Seo HJ
• Jung JH
• Song YT

Abstract

Prenatally diagnosed neuroblastomas have been reported in increasing numbers over the past several years. The vast majority are in favorable stages of the disease (stage I, II, IV-S). The authors experienced one case of stage IV-S neuroblastoma of the adrenal gland with liver metastasis, which regressed spontaneously after removal by adrenalectomy. This patient was noticed to have an abdominal mass at prenatal ultrasonography performed at 36weeks of gestation. This tumor was a neuroblastoma of the left adrenal gland with multiple liver metastases. Left adrenalectomy and liver biopsy were performed at 3 months of age. Thirty-eight months after surgery, an MRI demonstrated that the hepatic metastatic lesions had completely regressed without chemotherapy or radiation.

Keyword

Neuroblastoma; Prenatal diagnosis; Stage IV-S; Spontaneous regression

MeSH Terms

Adrenal Glands
Adrenalectomy*
Biopsy
Drug Therapy
Humans
Liver*
Magnetic Resonance Imaging
Neoplasm Metastasis*
Neuroblastoma*
Pregnancy
Prenatal Diagnosis
Ultrasonography, Prenatal