J Vet Sci.  2018 Nov;19(6):782-787. 10.4142/jvs.2018.19.6.782.

Genomic analysis of Sheldrake origin goose hemorrhagic polyomavirus, China

• Wan C
• Chen C
• Cheng L
• Liu R
• Fu G
• Shi S
• Chen H
• Fu Q
• Huang Y

• KMID: 2427026
• DOI: http://doi.org/10.4142/jvs.2018.19.6.782

Abstract

Goose hemorrhagic polyomavirus (GHPV) is not a naturally occurring infection in geese in China; however, GHPV infection has been identified in Pekin ducks, a domestic duck species. Herein, we investigated the prevalence of GHPV in five domestic duck species (Liancheng white ducks, Putian black ducks, Shan Sheldrake, Shaoxing duck, and Jinyun Sheldrake) in China. We determined that the Jinyun Sheldrake duck species could be infected by GHPV with no clinical signs, whereas no infection was identified in the other four duck species. We sequenced the complete genome of the Jinyun Sheldrake origin GHPV. Genomic data comparison suggested that GHPVs share a conserved genomic structure, regardless of the host (duck or geese) or region (Asia or Europe). Jinyun Sheldrake origin GHPV genomic characterization and epidemiological studies will increase our understanding of potential heterologous reservoirs of GHPV.

Keyword

Sheldrake; genome; goose hemorrhagic polyomavirus

MeSH Terms

China*
Ducks
Epidemiologic Studies
Geese
Genome
Polyomavirus*
Prevalence

Figure

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  Fig. 1 Schematic organization of Sheldrake origin goose hemorrhagic polyomavirus (GHPV). The LTAg and STAg coding regions were complementary. Pos, positions; ORF, open reading frames.

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  Fig. 2 Phylogenetic relationship of goose hemorrhagic polyomaviruses (GHPVs) in this study, based on the alignment of genome (A) and LTAg protein (B) sequences. The Sheldrake origin GHPVs (JY140Ma and JY141Ma) are indicated with black circles (●). Reference sequences obtained from GenBank are indicated by the accession number. The GHPV host is followed by the GenBank accession number.

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