J Korean Pain Soc.  1998 Oct;11(2):321-325.

Continuous Subcutaneous Administration of Morphine Using Patient Controlled Analgesia Device for Control of Cancer Pain

• Lee C
• Lee KH
• Kim WT

Abstract

Most of the patients with pain resulting from advanced cancer need opioid for adequate analgesia. Various methods of drug administration to control the pain have been developed. One of them, continuous administration of intravenous morphine is used for more effective pain control in the patient with severe pain that cannot be satisfactorily controlled by other methods of morphine administration. But this is not a suitable method at home because of the possibility of serious infectious complications and the difficulty in managing intravenous access by untrained personnel. Continuous subcutaneous adminstration of drugs can not only overcome such disadvantages of continuous intravenous infusion but also get almost the same effect of pain control as continuous intravenous infusion, and allows opportunity to move freely and return home, improving quality of life. We used continuous subcutaneous morphine and metoclopramide in the patients with cancer pain via a portable PCA device, and accomplished satisfactory pain relief without significant side effect.

Keyword

Analgesics, morphine; Anesthetic technique, subcutaneous adminstration; Pain, cancer pain; Equipment, PCA device

MeSH Terms

Analgesia
Analgesia, Patient-Controlled*
Humans
Infusions, Intravenous
Metoclopramide
Morphine*
Passive Cutaneous Anaphylaxis
Quality of Life
Volunteers
Metoclopramide
Morphine