Korean J Dermatol.
1997 Dec;35(6):1258-1262.
A Case of Cutaneous Pleomorphic T-cell Lymphoma
- Affiliations
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- 1Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.
- 2Department of Pathology Seoul National University College of Medicine, Seoul, Korea.
Abstract
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Cutaneous T-cell lymphomas other than mycosis fungoides and Sezary syndrome are heterogeneous; they deseve further scientific attention about their natural history and effective therapy. Pleomorphic T-cell lymphoma is a recently defined lymphoma type that can occur in the skin. We report the case of a man in whom such a tumor manifested itself with multiple subcutaneous lesions. The skin biopsy specimen showed diffuse dermal infiltration of atypical lymphocytes with highly pleomorphic nuclei. Testing for the antibody against HTLV-1 was negative and immunohistochemical staiiiing was compatible with pleomorphic T-cell lymphoma.