Tuberc Respir Dis.  2002 Mar;52(3):260-264.

A Cse of Severe Bleomycin-Induved Pneumonitis at Non-Hodgkin's Lymphoma

Affiliations
  • 1Department of Internal Medicine, Ulsan University Hospital University of Ulsan College of Medicine, Ulsan, Korea. yjmin@uuh.ulsan.kr

Abstract

Bleomycin-induced pulmonary toxitity usually occurs in the elderly patients (graeatee than 70 years old), patients with a cumulative dose above 400 units, previous chest radiotherapy, oxygen therapy, and reanal failure. H owever, there are some reports of severe pneumonitis in that developed after dministering low bleomycin doses (less than 100 units). In sever bleomycin-induced pneumonitis in non-Hodgkin's lymphoma patients, the response to corticosteroid is poor and the mortality rate is very high, approximately 83%. Therefore, clinicians should have a low threshold for investigating and treating bleomycin-induced pneumonitis. Here, we report a case of severe bleomycin-induced pneumonitis as a complication of a non-Hodgkin's lymphoma treatment.

Keyword

Non-Hodgkin's lymphoma; Bleomycin; Pulmonary toxicty

MeSH Terms

Aged
Bleomycin
Humans
Lymphoma, Non-Hodgkin*
Mortality
Oxygen
Pneumonia*
Radiotherapy
Thorax
Bleomycin
Oxygen
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