Tuberc Respir Dis.
2002 Mar;52(3):260-264.
A Cse of Severe Bleomycin-Induved Pneumonitis at Non-Hodgkin's Lymphoma
- Affiliations
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- 1Department of Internal Medicine, Ulsan University Hospital University of Ulsan College of Medicine, Ulsan, Korea. yjmin@uuh.ulsan.kr
Abstract
- Bleomycin-induced pulmonary toxitity usually occurs in the elderly patients (graeatee than 70 years old), patients with a cumulative dose above 400 units, previous chest radiotherapy, oxygen therapy, and reanal failure. H owever, there are some reports of severe pneumonitis in that developed after dministering low bleomycin doses (less than 100 units). In sever bleomycin-induced pneumonitis in non-Hodgkin's lymphoma patients, the response to corticosteroid is poor and the mortality rate is very high, approximately 83%. Therefore, clinicians should have a low threshold for investigating and treating bleomycin-induced pneumonitis. Here, we report a case of severe bleomycin-induced pneumonitis as a complication of a non-Hodgkin's lymphoma treatment.
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