J Stroke.  2018 Jan;20(1):33-45. 10.5853/jos.2017.02810.

Heart Failure as a Risk Factor for Stroke

Affiliations
  • 1Division of Cardiology, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea. withnoel@empal.com

Abstract

Heart failure (HF) is one of the major causes of death worldwide. Despite the high incidence of stroke in patients with HF, there has been a controversy as to whether HF itself is a risk factor for stroke. Recently, there is a great deal of evidence that HF itself increases the risk of stroke. In previous studies, the benefit of warfarin for stroke prevention in patients with HF was offset by the risk of bleeding. In the era of non-vitamin K antagonist oral anticoagulants with low bleeding profiles, we can expect a more effective stroke prevention in patients with HF by selective anticoagulation. The purpose of this review is to describe the relationship between stroke and HF, which could be an unconventional risk factor and a potential intervention target for stroke prevention.

Keyword

Heart failure; Stroke; CHAâ‚‚DSâ‚‚-VASc score

MeSH Terms

Anticoagulants
Cause of Death
Heart Failure*
Heart*
Hemorrhage
Humans
Incidence
Risk Factors*
Stroke*
Warfarin
Anticoagulants
Warfarin
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