Neurointervention.  2018 Sep;13(2):117-123. 10.5469/neuroint.2018.00976.

In Vitro Evaluation of Fusiform-Shaped Stents for Wide-Neck Intracranial Aneurysm Treatment

• Jia ZY
• Jiang YY
• Woo JM
• Hwang SM
• Lim OK
• Kim TI
• Park JC
• Lee HS
• Kim ES
• Lee DH

• KMID: 2424060
• DOI: http://doi.org/10.5469/neuroint.2018.00976

Abstract

PURPOSE
Wide-neck aneurysms (WNAs) associated with a dilated parent artery (PA) are not uncommon morphological abnormalities and usually cause inappropriate wall apposition and incomplete neck coverage of a tubular stent in stent-assisted coiling of aneurysms. We aimed to introduce a fusiform-shaped stent (FSS) and test its effectiveness in treating intracranial WNAs associated with a dilated PA using a three-dimensional (3D) model.
MATERIALS AND METHODS
Two FSS types were designed with the middle one-third segment dilated by 10% (FSS10) and 20% (FSS20) and were compared with the tubular-shaped stent (TSS). A patient-specific 3D WNA model was prototyped and produced, and in vitro stent placement was performed. Angiographic images of the three stent types were analyzed and compared using predetermined parameters.
RESULTS
The stent lumens were significantly larger in FSS10 and FSS20 than in TSS in the middle segments (P=0.046), particularly FSS20 (P=0.018). The non-covered area at the ostium tended to be smaller in FSS10 and FSS20 than in TSS, but the difference was not significant (P>0.05). The stent length was significantly longer in FSS10 and FSS20 than in TSS. The stent cell size was significantly larger in FSS than in TSS.
CONCLUSION
Better vessel wall apposition and aneurysmal neck coverage was observed for FSS than for TSS. No significant difference was observed between FSS10 and FSS20.

Keyword

Intracranial aneurysm; Endovascular procedure; Stents; Self-expandable metal stent; Proof of concept experiment

MeSH Terms

Aneurysm
Arteries
Cell Size
Endovascular Procedures
Humans
In Vitro Techniques*
Intracranial Aneurysm*
Neck
Parents
Stents*

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