Nucl Med Mol Imaging.  2018 Oct;52(5):401-404. 10.1007/s13139-018-0545-6.

Fibrosing Mediastinitis: a Rare Cause of Unilateral Absent Lung Perfusion on a V/Q Scan

Affiliations
  • 1Division of Nuclear Medicine andMolecular Biology, Department of Radiology, Temple University Hospital, 3401 N. Broad Street, Philadelphia, PA 19104, USA. sdadparvar@gmail.com
  • 2Division of Breast Imaging, Department of Radiology, Temple University Hospital, 3401 N. Broad Street, Philadelphia, PA 19104, USA.

Abstract

We report a case of a 29-year-old female with a history of asthma, post-partumARDS, and pulmonary hypertension who presents with severe shortness of breath. The patient describes her shortness of breath as progressive over the past 10 years. Chest radiography and CT angiography of the thorax showed findings consistent with fibrosing mediastinitis with severe stenosis of the left main pulmonary artery. This resulted in appearance of unilateral absent left lung perfusion on quantitative Tc-99-MAA perfusion and Xe-133 ventilation (V/Q) scan.

Keyword

Ventilation and perfusion scan; Fibrosing mediastinitis; CTPA; Histoplasma; Mediastinal fibrosis

MeSH Terms

Adult
Angiography
Asthma
Constriction, Pathologic
Dyspnea
Female
Histoplasma
Humans
Hypertension, Pulmonary
Lung*
Mediastinitis*
Perfusion*
Pulmonary Artery
Radiography
Thorax
Ventilation
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