J Liver Cancer.  2018 Sep;18(2):162-167. 10.17998/jlc.18.2.162.

Complete Remission with Transarterial Chemoembolization in a Patient with Hepatocellular Carcinoma Who Showed Early Recurrence following Surgical Resection

• Kim HY
• Kim CW
• Kim S
• Lee SL
• Ku YM
• Won YD

• KMID: 2422630
• DOI: http://doi.org/10.17998/jlc.18.2.162

Abstract

Although surgical resection is a curative treatment option for solitary hepatocellular carcinoma, high recurrence rate contributes to dismal long-term prognosis after curative resection. Early recurrence within 2 years after surgery is associated with intrahepatic metastasis of primary tumor. Liver regeneration after hepatic resection can accelerate tumorigenesis in remnant liver. Treatment strategies for intrahepatic recurrence after curative resection include salvage transplantation, repeated resection, local ablation, and transarterial chemoembolization (TACE). Here, we report a 51-year-old male who was presented with a single large tumor located at segment 4. The patient was initially treated with surgical resection, but intrahepatic recurrence occurred only 4 months after surgery. He achieved complete remission with repeated TACE and has survived without recurrence for 4 years so far.

Keyword

Carcinoma, Hepatocellular; Surgery; Recurrence; Transarterial chemoembolization

MeSH Terms

Carcinogenesis
Carcinoma, Hepatocellular*
Humans
Liver
Liver Regeneration
Male
Middle Aged
Neoplasm Metastasis
Prognosis
Recurrence*