Nat Prod Sci.  2018 Sep;24(3):213-218. 10.20307/nps.2018.24.3.213.

A New Flavonol Glycoside from Tristemma hirtum (Melastomataceae)

• Kenfack JN
• Ponou BK
• Kühlborn
• Teponno RB
• Nono RN
• Fouedjou R
• Opatz T
• Park HJ
• Tapondjou

• KMID: 2422015
• DOI: http://doi.org/10.20307/nps.2018.24.3.213

Abstract

Chemical investigation of the plant Tristemma hirtum P. Beauv (Melastomataceae) resulted to the isolation of a new flavonol glycoside named quercetin-7-O-α-D-arabinofuranoside (1), together with nine known compounds including 3"²-hexadecanoyl-2"²-(9aZ)-tetradecanoyl-glycerol 1"²-O-[β-D-galactopyranosyl-(1"³â†’ 6"³)-α-D-galactopyranoside] (2), arjunolic acid (3), β-sitosterol-3-O-β-D-glucopyranoside (4), terminolic acid (5), quercetin (6), asiatic acid (7), maslinic acid (8), 1β-O-galloylpedunculagin (9) and 6-hydroxyapigenin 7-O-β-D-glucopyranoside (10) from the methanol extract using normal and reversed phase column chromatography. The structures of these compounds were determined by comprehensive interpretation of their spectral data mainly including 1D- 2D-NMR (¹H-¹H COSY, HSQC, and HMBC) spectroscopic and ESI-TOF-MS mass spectrometric analysis.

Keyword

Tristemma hirtum; Melastomataceae; flavonol glycoside

MeSH Terms

Chromatography
Melastomataceae
Methanol
Plants
Quercetin
Methanol
Quercetin

Figure

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  Fig. 1. Chemical structures of compounds isolated from T. hirtum.

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  Fig. 2. Selected HMBC and COSY 1 H-1 H correlations of compound 1.

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