Infect Chemother.  2018 Sep;50(3):210-218. 10.3947/ic.2018.50.3.210.

Klebsiella pneumoniae Liver Abscess

• Jun JB

• KMID: 2420905
• DOI: http://doi.org/10.3947/ic.2018.50.3.210

Abstract

Since the mid 1980s, the prevalence of liver abscess caused by hypervirulent Klebsiella pneumoniae strain has increased in Asia, particularly in Taiwan and Korea. This strain is mostly K1 or K2 serotype, and has hypercapsular and hypermucoid phenotypes. Most infections are community acquired, and patients rarely have a hepatobiliary disease prior to infection. Clinical manifestations are characterized by fever and high C-reactive protein, and metastatic infections, such as septic emboli in the lung and endophthalmitis and meningitis are frequently observed. Antibiotic resistance is rare. Antibiotic treatment and abscess drainage are needed, and early diagnosis and treatment of endophthalmitis is also important.

Keyword

Liver Abscess; Klebsiella pneumoniae; C-reactive protein

MeSH Terms

Abscess
Asia
C-Reactive Protein
Drainage
Drug Resistance, Microbial
Early Diagnosis
Endophthalmitis
Fever
Humans
Klebsiella pneumoniae*
Klebsiella*
Korea
Liver Abscess*
Liver*
Lung
Meningitis
Phenotype
Prevalence
Serogroup
Taiwan
C-Reactive Protein

Figure

• 

  Figure 1 Routes of Infection (adapted from reference 8).

• 

  Figure 2 Mucoid phenotype of Klebsiella pneumoniae (adapted from reference 30).

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